PUBLICATION
SMC Laboratories is highly regarded worldwide as a consulting CRO that designs studies in line with the demands of pharmaceutical companies and research institutions.
In particular, in the NASH-HCC field, SMC is a highly regarded CRO, because of our unique STAM™ mice.
The results achieved with our STAM™ have been introduced in academic publications as well as scientific conferences.
Publications
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
No.63
Cell Mol Gastroenterol Hepatol.,
"Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in Mice" (Cell Mol Gastroenterol Hepatol. DOI: 10.1016/j.jcmgh.2020.10.010., 2020)
VIEW ARTICLE 
No.62
Journal of Lipid Research.,
“Insulin resistance dysregulates CYP7B1 leading to oxysterol accumulation: a pathway for NAFL to NASH transition” (J Clin Exp Gastroenterol., DOI: 10.1194/jlr.RA120000924., 2020)
VIEW ARTICLE
No.61
Clinical and Experimental Gastroenterology.,
“Changes in Function and Dynamics in Hepatic and Splenic Macrophages in Non-Alcoholic Fatty Liver Disease” (Clin Exp Gastroenterol., DOI: 10.2147/CEG.S248635., 2020)
VIEW ARTICLE
No.60
Purinergic Signalling,
“Design and in vivo activity of A3 adenosine receptor agonist prodrugs” (Purinergic Signal., DOI: 10.1007/s11302-020-09715-0., 2020)
VIEW ARTICLE
No.59
Cell Reports Medicine,
“Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis” (Cell Rep Med ., DOI: DOI: 10.1016/j.xcrm.2020.100056., 2020)
VIEW ARTICLE
No.58
Journal of Biochemical and Molecular Toxicology,
“Omaveloxolone and TX63682 Are Hepatoprotective in the STAM™ Mouse Model of Nonalcoholic Steatohepatitis” (J Biochem Mol Toxicol., DOI: 10.1002/jbt.22526., 2020)
VIEW ARTICLE
No.57
Journal of Medicinal Chemistry,
“6-Amino[1,2,5]oxadiazolo[3,4-b]pyrazin-5-ol Derivatives as Efficacious Mitochondrial Uncouplers in STAM Mouse Model of Nonalcoholic Steatohepatitis” (J Med Chem., DOI: 10.1021/acs.jmedchem.0c00542., 2020)
VIEW ARTICLE
No.56
Scientific Reports,
“Novel Combinatorial Regimen of Garcinol and Curcuminoids for Non-alcoholic Steatohepatitis (NASH) in Mice” (Sci Rep., DOI: 10.1038/s41598-020-64293-w)
VIEW ARTICLE
No.55
Journal of Medicinal Chemistry,
“[1,2,5]Oxadiazolo[3,4-b]pyrazine-5,6-diamine Derivatives as Mitochondrial Uncouplers for the Potential Treatment of Nonalcoholic Steatohepatitis” (J Med Chem., DOI: 10.1021/acs.jmedchem.9b01440., 2020)
VIEW ARTICLE
No.54
Diabetology & Metabolic Syndrome,
“Intracellular toxic advanced glycation end-products (TAGE) in myoblasts may cause sarcopenia: Research article of a non-clinical study” (Diabetol. Metab. Syndr., DOI: 10.21203/rs.2.23269/v1, 2020)
VIEW ARTICLE
No.53
European Radiology Experimental,
“Free fatty acid-based low-impedance liver image: a characteristic appearance in nonalcoholic steatohepatitis (NASH)” (Eur Radiol Exp., 4: 3., 2020)
VIEW ARTICLE
No.52
Journal of medicinal chemistry,
“Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis.” (J Med Chem., DOI: 10.1021/acs.jmedchem.9b01621., 2020)
VIEW ARTICLE
No.51
Expert Opinion on Investigational Drugs,
“Pegbelfermin (BMS-986036): an investigational PEGylated fibroblast growth factor 21 analogue for the treatment of nonalcoholic steatohepatitis.” (Expert Opin Investig Drugs. 3:1-9., 2020)
VIEW ARTICLE
No.50
JHEP Reports,
“A Blocking Monoclonal Antibody to CCL24 Alleviates Liver Fibrosis and Inflammation in Experimental Models for Liver Damage” (JHEP Reports, 10.1016/j.jhepr.2019.100064, 2020)
VIEW ARTICLE