PRESENTATION

SMC Laboratories is highly regarded worldwide as a consulting CRO that designs studies in line with the demands of pharmaceutical companies and research institutions.
In particular, in the MASH/NASH field, SMC is a highly regarded CRO, because of our unique STAM™ mice.
The results achieved with our STAM™ have been introduced in academic publications as well as scientific conferences.

Presentations

2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

No.27

2014

AASLD 2014,

“L-carnitine prevents progression of non-alcoholic steatohepatitis in a mouse model with upregulation of mitochondrial pathway“ Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences

No.26

2014

AASLD 2014,

“MN-001 (tipelukast), a novel, orally bioavailable drug, reduces fibrosis and inflammation and down-regulates TIMP-1, collagen Type 1 and LOXL2 mRNA overexpression in an advanced NASH (nonalcoholic steatohepatitis) model“ MediciNova, Inc.

No.25

2014

ICLAF 2014,

“MN-001 (tipelukast), a nonselective phosphodiesterase, 5-lipoxygenase, leukotriene, phospholipase C and thromboxane A2 inhibitor, demonstrates anti-fibrotic effects in the bleomycin-induced idiopathic pulmonary fibrosis mouse model“ MediciNova, Inc.

No.24

2014

ADA 2014,

“Liraglutide prevents steatohepatitis, liver fibrosis, and accompanying carcinogenesis in a diabetes and nonalcoholic steatohepatitis mouse model treated with STZ-HFD“ Saga University

No.23

2014

ATS 2014,

“Solithromycin Reduces Inflammation In Mice Caused By Bleomycin-Induced Lung Injury“ Cempra, Inc.

No.22

2014

DDW 2014,

“Anti-NASH Effects of Solithromycin in NASH-HCC Mouse Model“ Cempra, Inc.

No.21

2014

AACR 2014,

“Clinicopathological characterization of non-alcoholic Steatohepatitis (NASH)-derived Hepatocellular carcinoma (HCC) as a patient stratification model in mice)” The Jikei University School of Medicine

No.20

2014

Keystone Symposia 2014,

“The NADPH Oxidase (NOX) Inhibitor GKT137831 Alleviates Liver Inflammation and Fibrosis in a Mouse Model of Non-Alcoholic Steatohepatitis (NASH)” Genkyotex S.A.