Preclinical HCC study with positive control, Lenvatinib
We recently obtained new evaluation data on the Lenvatinib in our STAM model and it shows significantly improving effects on the Number, Size and Growth Rate of the tumor nodules in the liver as well as on the overall survival. (Please see the data below)
The significance of a positive control in a drug efficacy evaluation study is to demonstrate the efficacy of the test substance to the same degree as a known effective treatment and to demonstrate the efficacy of the test treatment by showing the superiority of the test treatment in direct comparison with the positive control. In other words, by establishing a positive control, the drug efficacy of the test substance can be evaluated by comparing it to the positive control.
Why not use this positive control to carry out a drug efficacy evaluation study of your test substance?