Introduction of Bile duct ligation (BDL)-induced primary biliary cirrhosis model
Today, we would like to introduce our bile duct ligation (BDL)-induced primary biliary cirrhosis disease model.
This BDL model reproduces the pathological features of cholestatic liver disease, which leads to acute liver injury followed by liver inflammation and severe fibrosis.
It is a great model for those looking to conduct in-vivo screening studies for drug candidates with hepatoprotective, anti-inflammatory and anti-fibrotic properties, as it has a relatively short study period of only 2 weeks.
If you would like to test your drug candidate in model other than the BDL model, we also have a variety of other fibrotic and inflammatory disease models in addition to the BDL model, and would be happy to use our drug evaluation services to aid you in your drug discovery journey.