2025.01.29

Pre-clinical studies for Cholestatic Liver Diseases: Bile Duct Ligation model

We would like to share with you about our Bile duct ligation (BDL) model, known as a disease model mice for cholestatic liver disease.
 
This model reproduces the pathological features of cholestatic liver disease, which leads to acute liver injury followed by liver inflammation and severe fibrosis.

 

It is a useful model for those looking to evaluate hepatoprotective, anti-inflammatory and anti-fibrotic properties of drug candidates in a short period.

If you would like to test your drug candidate in model other than the BDL model, we also have a variety of other fibrotic and inflammatory disease models in addition to the BDL model, and would be happy to use our drug evaluation services to aid you in your drug discovery journey.

If this is something you might be interested in, please feel free to let me know.