One of our clients published preclinical data on the FASEB Journa
One of our clients FDA-National Center for Toxicological Research (NCTR) has published the results of a study using STAMTM model on The FASEB Journal.
Title: “Epigenetically mediated inhibition of S-adenosylhomocysteine hydrolase and the associated dysregulation of 1-carbon metabolism in nonalcoholic steatohepatitis and hepatocellular carcinoma”
By using STAMTM model (NASH-HCC model), they demonstrated that advanced NASH and NASH-related liver carcinogenesis are characterized by a significant dysregulation of 1-carbon homeostasis.