Imiquimod (IMQ)-induced psoriasis model
We are pleased to announce that starting today we are expanding our preclinical services and adding the “Imiquimod (IMQ)-induced dermatitis model“, a mouse model for psoriasis, to our lineup.
Psoriasis is a refractory skin disease that is caused by both genetic and environmental factors. It causes chronic inflammation characterized by the clinical appearance of erythema and scaling of the skin.
The prevalence of psoriasis ranges from 2-4%, making psoriasis a serious global problem with at least 100 million individuals affected worldwide.
Presently there are no treatments that completely cure psoriasis, with current therapy options only managing the symptoms of the disease.
The IMQ model is one of the most widely used models for psoriasis research. The model shows keratinocyte hyperproliferation, immune cells infiltration, and activated IL-17/IL-23 axis, as seen in human psoriasis patients.
In addition to the IMQ model, we also have a variety of other fibrotic and inflammatory disease models.
If you would like to learn more about our services or the IMQ model, please don’t hesitate to contact us!