Expanding Our IPF Services: Introducing Male Mouse Models for Drug Efficacy Evaluation Studies
We would like to inform you that we have extended our drug efficacy evaluation study services for male bleomycin (BLM)-induced lung fibrosis mouse model.
Idiopathic pulmonary fibrosis (IPF) is a lung disease that causes fibrosis in the lungs, and is more common in men than in women. Until now, we have primarily used female mice for drug efficacy evaluation studies due to the ease of handling and control of mortality rates. However, in response to the clients’ desire to take into gender differences in physiological conditions and compound mechanisms of action in the preclinical stage, we added the option to use male mice for the BLM model in addition to the existing BLM model using female mice.
We have been actively working on obtaining data with male mice and have confirmed that the pathology is indeed stronger, which is consistent with the public data available. As a result, we are now prepared to offer the option to conduct drug efficacy evaluation studies using male IPF model mice, providing a more comprehensive understanding of the potential therapeutic interventions for IPF.