Our Focus on Immuno-Oncology
The utilization of STAM™ mouse enables non-clinical research for the development of liver cancer therapeutics targeting immune cells, tumor microenvironment, and genetic mutations.
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In addition to the liver disease area that we focus on, we also provide non-clinical pharmacology studies for various other disease areas.
The STAM™ mouse is our in-house developed model. It is a MASH-HCC model with a diabetes background. So far, we have over 15 MOA categories and more than 270 target molecules of test substances that we have evaluated using STAM™ mice.
We offer various disease mice models related to inflammation, fibrosis, metabolic disorders, cancer, or cancer immunity, as well as STAM™ model, which is a world's first MASH (metabolic dysfunction-associated steatohepatitis) mouse model that we have developed.
Results of non-clinical pharmacology studies by our company have been presented at many major academic conferences in the United States and Europe, such as DDW, AASLD, EASL, ADA, or AACR. It has also been published in journals such as PNAS, Hepatology, or Cell metabolism.
We are a consulting-type non-clinical CRO, meaning that we design in-vivo studies with clients’ requests. We have been supporting their cutting-edge research on non-clinical pharmacology study.
Here, we can share some data for clinical correlation between the results of our non-clinical studies using STAM™ mice and the results of clinical studies.
We provide services that utilize our technology and know-how regarding inflammation, fibrosis, metabolic disorder, cancer, and cancer immunity.
Our service and disease mouse models bridge the development of the next- Generation Cancer Therapies in the field of Immuno-oncology.
At SMC Laboratories, we support drug research with our cutting-edge non-clinical pharmacology studies to quickly deliver therapeutic drugs to patients suffering from diseases that cannot be treated with existing drugs.
We, SMC Laboratories, are highly regarded worldwide as a consulting – based CRO that designs tailored to the needs of pharmaceutical companies and research institutions.
Published papers
PNAS, Oncotarget, Hepatology, Plos One etc.
Published presentation
DDW, AASLD, EASL, AACR etc.